INTEGRATED ANTIBODY TECHNOLOGIES
Technology
Discovery, internalization, and Fc engineering for differentiated antibody therapeutics
01
HMX Discovery Engine
Antibody Discovery Platform
HMX Discovery Engine is HumiNex’s antibody discovery platform designed to identify differentiated antibodies against challenging membrane protein targets, including GPCRs.
- Antibody discovery against complex membrane protein targets
- Library-based screening and selection of target-specific binders
- Lead optimization through affinity maturation and functional evaluation
02
ISP
Internalization Shuttle Platform
ISP is a bispecific antibody platform designed to enhance the internalization of poorly internalizing membrane targets by engaging them with highly internalizing cell-surface receptors.
-
Bispecific engagement of target and internalizing shuttle receptors
-
Enhanced internalization of poorly internalizing membrane targets
-
Designed to support efficient intracellular delivery of antibody-based therapeutics
03
ExFc
Fc Engineering Platform
ExFc is an Fc engineering platform designed to optimize pharmacokinetic properties and modulate effector functions through the selection of engineered Fc variants for differentiated antibody therapeutics.
-
Diverse library of engineered Fc variants
-
Optimization of pharmacokinetic properties
-
Tailored modulation of Fc-mediated effector functions
